Howdy
Never done one. But you could put any kind of site on it that you want as long as you're willing to do some machining. Also it might look kind of goofy since the Detonics slide is cut ramped up to the base site base. I do allot of pistol work and I think the best site for these guns is probably the ones they came with. Or none at all, ie MKVII.
Hope this helps.
L8r
Conley Janssen
USMC 87-93